In 1987, responding to widespread concern about America's competitiveness and future in the development of space technology and the academic preparation of our next generation of space professionals, NASA initiated a program to establish Space Engineering Research Centers (SERC's) at universities with strong doctoral programs in engineering. The goal was to create a national infrastructure for space exploration and development, and sites for the Centers would be selected on the basis of originality of proposed research, the potential for near-term utilization of technologies developed, and the impact these technologies could have on the U.S. space program. The Centers would also be charged with a major academic mission: the recruitment of topnotch students and their training as space professionals. This document describes the goals, accomplishments, and benefits of the research activities of the University of Arizona/NASA SERC. This SERC has become recognized as the premier center in the area known as In-Situ Resource Utilization or Indigenous Space Materials Utilization.