Combines basic science and clinical medicine in a concise, easy-to-read format. Fully revised and updated, it reflects the latest information on genetic and molecular biology and integrates even more clinical medicine into the text. Features case histories, advanced concept boxes, and color illustrations that clarify complex biochemical concepts. Summary boxes and an expanded self-assessment section make the text useful for review and study
Includes bibliographical references and index
Introduction -- Amino acids and proteins -- Blood: cells and plasma proteins -- Oxygen transport -- Catalytic proteins-enzymes -- Hemostasis and thrombosis -- Membranes and transport -- Bioenergetics and oxidative metabolism -- Function of the gastrointestinal tract -- Micronutrients: vitamins and minerals -- Anaerobic metabolism of glucose in the blood cell -- Carbohydrate storage and synthesis in liver and muscle -- The tricarboxylic acid cycle -- Oxidative metabolism of lipids in liver and muscle -- Biosynthesis and storage of fatty acids in liver and adipose tissue -- Biosynthesis of cholesterol and steroids -- Lipids and lipoproteins -- Biosynthesis and degradation of amino acids -- Muscle: energy metabolism and contraction -- Glucose homeostasis, fuel metabolism, and insulin -- Nutrition -- Water and electrolyte balance: kidney function -- Lung and kidney: the control of acid-based balance -- Calcium and bone metabolism -- Complex carbohydrates: glycoproteins -- Complex lipids -- The extracellular matrix -- Special liver function -- Biosynthesis and degradation of nucleotides -- Deoxyribonucleic acid (DNA) -- Ribonucleic acid (RNA) -- Protein synthesis and turnover -- Control of gene expression -- Recombinant DNA technology -- Oxygen and life -- The immune response -- Biochemical endocrinology -- Membrane receptors and signal transduction -- Neurochemistry -- Neurotransmitters -- Cell growth, differentiation, and cancer -- Aging
