Preprint articles are preliminary scientific manuscripts or reports that have not been peer-reviewed yet. The aim of this study is to describe study characteristics of preprint articles and to assess how results and conclusions change in relation to the corresponding peer-reviewed article. As the use of preprints in prevention research has been overlooked so far, we aim to investigate how different fields of prevention preprints, for example immunizations, counselling, screening or chemoprevention, compare with each other. We furthermore aim to describe the proportion of preprint articles that remain unpublished, and assess the risk of bias of preprint articles and compare them to published scientific articles in the field of prevention research.

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