The aim of the present study is to examine the extent to which religiosity of individuals is related to stress reactivity in the face of psychological and emotional stress exposure. It will be investigated in more detail whether religious people show a lower stress reactivity with regard to these physiological parameters than non-religious people. Previous research has demonstrated that religion has positive effects on health-related constructs such as life satisfaction, coping as well as social support, and leads furthermore to a reduction in the chronic experience of stress. These constructs are explored in more detail in relationship to religion to support these findings, considering the role of perceived social support as a possible mediator. The expression of schizotypy is also taken into account to control for its possible influence in relation to the effects of religiosity and to ensure that these impacts are specific to religion.