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Dec 21, 2018
12/18
by
Neidle, Stephen
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ix, 108 pages : 23 cm
Topics: {u'11': u'Moleku\u0308lstruktur', u'10': u'Molekulare Erkennung', u'12': u'DNA Analysis', u'1':...
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50
Oct 26, 2014
10/14
by
Todd, Alan K.; Neidle, Stephen
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This article is from Nucleic Acids Research , volume 39 . Abstract The knowledge that potential guanine quadruplex sequences (PQs) are non-randomly distributed in relation to genomic features is now well established. However, this is for a general potential quadruplex motif which is characterized by short runs of guanine separated by loop regions, regardless of the nature of the loop sequence. There have been no studies to date which map the distribution of PQs in terms of primary sequence or...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130275
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Oct 27, 2014
10/14
by
Islam, Barira; Sgobba, Miriam; Laughton, Charlie; Orozco, Modesto; Sponer, Jiri; Neidle, Stephen; Haider, Shozeb
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This article is from Nucleic Acids Research , volume 41 . Abstract The human telomeric DNA sequence with four repeats can fold into a parallel-stranded propeller-type topology. NMR structures solved under molecular crowding experiments correlate with the crystal structures found with crystal-packing interactions that are effectively equivalent to molecular crowding. This topology has been used for rationalization of ligand design and occurs experimentally in a number of complexes with a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575793
